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Purpose and Description
The Microdialysis Focus Group of the AAPS aims to be a stimulant and vehicle for
the exchange of information and discussions on the microdialysis technique with
respect to its important current applications and future potentials in quantitative
drug research and development.
Within the last decades it has become clear that in vivo microdialysis is of unique
value in quantitative pharmacological research. It is the only in vivo technique
that is able to provide temporal information on local free concentrations of drugs
and metabolites in the extracellular space at specific sites in the body. Thus,
quantitative in vivo microdialysis studies have provided new information on drug
delivery to, for example, the CNS and subcutaneous sites, on distribution to the
liver, lung, muscle, adipose and other target tissues, as well as on the characterization
of blood levels of drug and metabolites. The microdialysis technique is therefore
closely connected to the research fields of drug delivery, drug metabolism, pharmacokinetics,
and pharmacodynamics, while the state-of-art analytical technologies are needed,
and expansion of microdialysis applications will follow progress in analytical technologies.
This explains the Section Affiliations of the AAPS indicated above.
The Membership of the Microdialysis Focus Group is open to any AAPS member who has
an interest in microdialysis, and in time, the Members has exceeded the number of
250. The Focus Group Chair and Steering Committee hope to serve the Microdialysis
Focus Group Members by organizing podium and poster presentations, symposia, and
other mechanisms for adequate exchange of information. We are very much open to
suggestions from the Microdialysis Focus Group Members.
Newsletter
JOIN THE MICRODIALYSIS FOCUS GROUP
To join the Microdialysis Focus Group, click
here.
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